PDGFRb, Recombinant, Human, Active (PDGFR beta, Beta-type Platelet-derived Growth Factor Receptor, Platelet-derived Growth Factor Receptor beta)
Catalog No : USB-220145
560.94€
0.00€
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| Product name | PDGFRb, Recombinant, Human, Active (PDGFR beta, Beta-type Platelet-derived Growth Factor Receptor, Platelet-derived Growth Factor Receptor beta) | ||
|---|---|---|---|
| Catalog No | USB-220145 | ||
| Supplier’s Catalog No | 220145 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Baculovirus (Sf9 insect cells) | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 96 | ||
| Storage | -70°C | ||
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| Other names | |||
| Grade | Purified | ||
| Purity | ~90% (SDS-PAGE) | ||
| Form | Supplied as a liquid in 50mM Tris-HCl, pH 7.5, 150mM sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~90% (SDS-PAGE) | ||
| Description | PDGFRb (platelet-derived growth factor receptor b) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. PDGFRb deficient mice are hemorrhagic, severely anemic and exhibit a defect in kidney glomeruli function. However, absence of PDGFRb has no impact on major blood vessels and the heart. PDGFRb expression and activity is elevated in several cancers and inhibition of PDGFRb activity blocks progression of renal carcinoma in an animal model. Source: Recombinant protein corresponding to human PDGFR beta, expressed in Baculovirus (Sf9 insect cells). Molecular Weight: ~96kD Specific Activity: ~20nmol/min/mg Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | ||
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