Prolactin Receptor, Recombinant, Human (PRL-R, hPRLrI, PRL, Luteotropic Hormone, LTH, PRLR, PRL R)
Catalog No : USB-220196
501.16€
0.00€
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| Product name | Prolactin Receptor, Recombinant, Human (PRL-R, hPRLrI, PRL, Luteotropic Hormone, LTH, PRLR, PRL R) | ||
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| Catalog No | USB-220196 | ||
| Supplier’s Catalog No | 220196 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 23.97 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~97% (SDS-PAGE, HPLC) | ||
| Form | Supplied as a lyophilized powder in 0.0045mM NaHCO3. No preservative added. Reconstitute with sterile ddH2O to 0.1-1mg/ml | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~97% (SDS-PAGE, HPLC) | ||
| Description | Prolactin is a pituitary hormone that plays a role in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The primary step in its action is the binding to a specific membrane receptor (prolactin receptor) which belongs to the superfamily of class 1 cytokine receptors. Prolactin is a hormone involved in a range of significant functions including ion transport and osmoregulation, stimulation of milk, protein synthesis as well as the regulation of numerous reproductive functions. Prolactin exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane Prolactin receptor. PRLR varies in size (short and long forms) with tissue source and species, from ~40kD-100kD. Source: Recombinant protein corresponding to the extracellular domain of human Prolactin Receptor, a non-glycosylated, polypeptide chain containing 210aa, expressed in E. coli. Molecular Weight: ~23.97kD Biological Activity: Determined by the dose-dependent inhibition of Prolactin stimulated proliferation of Nb2 cells and by high affinity binding of ovine Prolactin and other lactogenic hormones in 1:1 molar ratio. Endotoxin: <0.1ng/ug Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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