KLRB1, Recombinant, Human, His-Tag (Killer Cell Lectin-like Receptor Subfamily B Member 1, CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A, NKRP1A)
Catalog No : USB-301240
560.94€
0.00€
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| Product name | KLRB1, Recombinant, Human, His-Tag (Killer Cell Lectin-like Receptor Subfamily B Member 1, CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A, NKRP1A) | ||
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| Catalog No | USB-301240 | ||
| Supplier’s Catalog No | 301240 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 21 | ||
| Storage | -70°C | ||
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| Other names | |||
| Grade | Purified | ||
| Purity | ~85% (SDS-PAGE) | ||
| Form | Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.4M urea, 10% glycerol. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~85% (SDS-PAGE) | ||
| Description | Killer cell lectin-like receptor subfamily B member 1, also known as KLRB1, plays an inhibitory role on natural killer (NK) cells cytotoxicity. Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C-terminus. Recombinant human KLRB1 protein, fused to His-tag at N-terminus, was expressed in E. coli. Source: Recombinant protein corresponding to 183aa and aa67-225 of human KLRB1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~21kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSM QKSSIE KCSVDIQQSR NKTTERPGLL NCPIYWQQLR EKCLLFSHTV NPWNNSLADC STKESSLLLI RDKDELIHTQ NLIRDKAILF WIGLNFSLSE KNWKWINGSF LNSNDLEIRG DAKENSCISI SQTSVYSEYC STEIRWICQK ELTPVRNKVY PDS Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | ||
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