BMPR1B, Recombinant, Human, aa14-126, His-Tag (Bone morphogenetic protein receptor type-1B isoform b)

Catalog No : USB-349731
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Product name BMPR1B, Recombinant, Human, aa14-126, His-Tag (Bone morphogenetic protein receptor type-1B isoform b)
Catalog No USB-349731
Supplier’s Catalog No 349731
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 15.1
Storage -20°C
Other names
Grade Purified
Purity ~80% (SDS-PAGE)
Form Supplied as a liquid in PBS, pH 7.4, 1mM DTT, 0.1mM PMSF, 20% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~80% (SDS-PAGE)
Description BMPR1B also known as bone morphogenetic protein receptor type-1B isoform b. BMPR1B is on ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. It's receptor for BMP7/OP-1 and GDF5. Source: Recombinant protein corresponding to aa14-126 of human BMPR1B, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~15.1kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED DSGLPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD GPIHHR Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.