LAIR-1, Recombinant, Human, aa22-125 (Leukocyte-associated immunoglobulin-like receptor 1 isoform a, LAIR1, CD305)

Catalog No : USB-350027
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Product name LAIR-1, Recombinant, Human, aa22-125 (Leukocyte-associated immunoglobulin-like receptor 1 isoform a, LAIR1, CD305)
Catalog No USB-350027
Supplier’s Catalog No 350027
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 11.7
Storage -20°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris, pH 7.5, 50mM sodium chloride, 1mM EDTA.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description LAIR-1 is a glycoprotein (~32kD) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells , B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. Source: Recombinant protein corresponding to aa22-125 of human LAIR-1 expressed in E. coli. Molecular Weight: ~11.7kD AA Sequence: MQEEDLPRPS ISAEPGTVIP LGSHVTFVCR GPVGVQTFRL ERESRSTYND TEDVSQASPS ESEARFRIDS VSEGNAGPYR CIYYKPPKWS EQSDYLELLV KETSG Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.