RARalpha, Recombinant, Human, aa68-173, His-Tag (Retinoic acid receptor, alpha isoform 1)

Catalog No : USB-350229
508.06€
0.00€

Shipping cost plus VAT not included , delivery in 7-14 business days

Product name RARalpha, Recombinant, Human, aa68-173, His-Tag (Retinoic acid receptor, alpha isoform 1)
Catalog No USB-350229
Supplier’s Catalog No 350229
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 14
Storage -20°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris, pH 7.5, 0.1M sodium chloride, 5mM beta-mercaptoethanol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description Retinoic acid receptors (RAR) belong to the large family of ligand responsive gene regulatory proteins that includes receptors for steroid and thyroid hormones. These proteins contain two highly conserved domains that are involved in determining their DNA and ligand-binding activities. Three isotypes of RARs, alpha, beta, and gamma, are encoded by distinct genetic loci and possess distinct transcriptional properties. Typically, RAR-alpha represses target gene transcription in the absence of hormone, whereas RAR-beta and gamma fail to repress under these conditions. Source: Recombinant protein corresponding to aa68-173 of human RARalpha, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~14kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MSEEIVPSPP SPPPLPRIYK PCFVCQDKSS GYHYGVSACE GCKGFFRRSI QKNMVYTCHR DKNCIINKVT RNRCQYCRLQ KCFEVGMSKE SVRNDRNKKK KEVPKPE Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.