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Categories: Peptides & Proteins / Proteins

Product name			Formyl Peptide Receptor-like 1, Control Peptide
Catalog No			USB-F6010-10A1
Supplier’s Catalog No			F6010-10A1
Supplier			US Biologicals
Source antigen
Reactivity			human Formyl Peptide Receptor-Like 1 (FPRL1) at ~38kD.
Cross reactivity			Human,
Applications
Molecular weight

Storage			-20°C
Other names
Grade			Highly Purified
Purity			95+% HPLC, Mass Spec
Form			Supplied as a white to off-white lyophilized powder.
Reactivity life			12 months
Note			For reserch purpose only
Purity			95+% HPLC, Mass Spec
Description			FPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries. Sequence: The sequence ASWGGTPEERLKC corresponds to amino acids 181-192 of FPRL1, plus one added Cysteine residue. Applications: Control Peptide for anti-FPRL1, Cat#F6010-10A Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.