Erythropoietin Receptor, Recombinant, Human, aa25-250, His-Tag (EPO-R, EPOR)
Catalog No : USB-351214
508.06€
0.00€
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| Product name | Erythropoietin Receptor, Recombinant, Human, aa25-250, His-Tag (EPO-R, EPOR) | ||
|---|---|---|---|
| Catalog No | USB-351214 | ||
| Supplier’s Catalog No | 351214 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, human from insect cell line | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 25.6 | ||
| Storage | -20°C/-70°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~95% (SDS-PAGE) | ||
| Form | Supplied as a liquid in PBS, pH 7.4, 10% glycerol. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~95% (SDS-PAGE) | ||
| Description | EPOR, also known as Erythropoietin receptor, mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, it dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. So it may also activate the LYN tyrosine kinase. Source: Recombinant protein corresponding to aa25-250 from human EPOR, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~25.6kD (232aa) AA Sequence: APPPNLPDPK FESKAALLAA RGPEELLCFT ERLEDLVCFW EEAASAGVGP GNYSFSYQLE DEPWKLCRLH QAPTARGAVR FWCSLPTADT SSFVPLELRV TAASGAPRYH RVIHINEVVL LDAPVGLVAR LADESGHVVL RWLPPPETPM TSHIRYEVDV SAGNGAGSVQ RVEILEGRTE CVLSNLRGRT RYTFAVRARM AEPSFGGFWS AWSEPVSLLT PSDLDPHHHH HH Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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