IL21R, Recombinant, Human, aa20-232, His-Tag (Interleukin-21 Receptor, CD360, NILR)

Catalog No : USB-351308
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Product name IL21R, Recombinant, Human, aa20-232, His-Tag (Interleukin-21 Receptor, CD360, NILR)
Catalog No USB-351308
Supplier’s Catalog No 351308
Supplier US Biologicals
Source antigen Recombinant, human from insect cell line
Reactivity
Cross reactivity
Applications
Molecular weight 25.6
Storage -20°C/-70°C
Other names
Grade Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life 12 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description IL21R, also known as Interleukin-21 receptor, belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Source: Recombinant protein corresponding to aa20-232 from human IL21R, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~25.6kD (221aa) AA Sequence: CPDLVCYTDY LQTVICILEM WNLHPSTLTL TWQDQYEELK DEATSCSLHR SAHNATHATY TCHMDVFHFM ADDIFSVNIT DQSGNYSQEC GSFLLAESIK PAPPFNVTVT FSGQYNISWR SDYEDPAFYM LKGKLQYELQ YRNRGDPWAV SPRRKLISVD SRSVSLLPLE FRKDSSYELQ VRAGPMPGSS YQGTWSEWSD PVIFQTQSEE LKEVEHHHHH H Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.