KLRC2, Recombinant, Human, aa94-231, His-Tag (NKG2-C type II integral membrane protein, CD159c, NKG2-C, NKG2C)

Catalog No : USB-351330
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Product name KLRC2, Recombinant, Human, aa94-231, His-Tag (NKG2-C type II integral membrane protein, CD159c, NKG2-C, NKG2C)
Catalog No USB-351330
Supplier’s Catalog No 351330
Supplier US Biologicals
Source antigen Recombinant, human from E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 18.4
Storage -20°C/-70°C
Other names
Grade Purified
Purity ~85% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.4M urea, 10% glycerol.
Reactivity life 12 months
Note For reserch purpose only
Purity ~85% (SDS-PAGE)
Description NKG2-C type II integral membrane protein, also known as KLRC2, plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. Source: Recombinant protein corresponding to aa94-231 from human KLRC2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~18.4kD (162aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMIPFLEQ NNFSPNTRTQ KARHCGHCPE EWITYSNSCY YIGKERRTWE ESLLACTSKN SSLLSIDNEE EMKFLASILP SSWIGVFRNS SHHPWVTING LAFKHKIKDS DNAELNCAVL QVNRLKSAQC GSSMIYHCKH KL Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.