NGFR, Recombinant, Human, aa29-250, His-Tag (Tumor necrosis factor Receptor superfamily member 16, CD271, Gp80-LNGFR, p75(NTR), p75NTR, TNFRSF16)

Catalog No : USB-351390
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Product name NGFR, Recombinant, Human, aa29-250, His-Tag (Tumor necrosis factor Receptor superfamily member 16, CD271, Gp80-LNGFR, p75(NTR), p75NTR, TNFRSF16)
Catalog No USB-351390
Supplier’s Catalog No 351390
Supplier US Biologicals
Source antigen Recombinant, human from insect cell line
Reactivity
Cross reactivity
Applications
Molecular weight 24.6
Storage -20°C/-70°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life 12 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description NGFR, also known as tumor necrosis factor receptor superfamily member 16, is a member of the tumor necrosis factor receptor superfamily with a widespread pattern of expression in tissues such as the brain, liver, lung, and muscle. It plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. They are low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. It can mediate cell survival as well as cell death of neural cells. Source: Recombinant protein corresponding to aa29-250 from human NGFR, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~24.6kD(230aa) AA Sequence: KEACPTGLYT HSGECCKACN LGEGVAQPCG ANQTVCEPCL DSVTFSDVVS ATEPCKPC TE CVGLQSMSAP CVEADDAVCR CAYGYYQDET TGRCEACRVC EAGSGLVFSC QDKQNTVCEE CPDGTYSDEA NHVDPCLPCT VCEDTERQ LR ECTRWADAEC EEIPGRWITR STPPEGSDST APSTQEPEAP PEQDLIASTV AGVVTTVMGS SQPVVTRGTT DNLEHHHHHH Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.