Imugex

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Categories: Peptides & Proteins / Proteins

Product name			EGFR, Recombinant, Human, aa25-645, hIgG-His-Tag (Epidermal Growth Factor Receptor)
Catalog No			USB-369051
Supplier’s Catalog No			369051
Supplier			US Biologicals
Source antigen			Recombinant, human from CHO cell
Reactivity
Cross reactivity
Applications
Molecular weight			95.5

Storage			-20°C
Other names
Grade			Highly Purified
Purity			~90% (SDS-PAGE)
Form			Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~90% (SDS-PAGE)
Description			EGFR, also known as epidermal growth factor receptor, is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinase. This protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-alpha, betacellulin, etc. It can also be recruited to form heterodimers with the ligand activated ErbB3 or ErbB4. EGFR signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. It is overexpressed in a wide variety of tumors and is the target of several anti-cancer drugs. Source: Recombinant protein corresponding to aa25-645 from human EGFR, fused to hlg-His-Tag at C-terminal, expressed in CHO cell. Molecular Weight: ~95.5kD (860aa) 100-150KD (SDS-PAGE under reducing conditions.) Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.