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Categories: Peptides & Proteins / Proteins

Product name			FGFR4, Recombinant, Human, aa22-369, His-Tag (Fibroblast Growth Factor Receptor 4 Isoform 1)
Catalog No			USB-369059
Supplier’s Catalog No			369059
Supplier			US Biologicals
Source antigen			Recombinant, human from insect cell line
Reactivity
Cross reactivity
Applications
Molecular weight			39.5

Storage			-20°C
Other names
Grade			Highly Purified
Purity			~90% (SDS-PAGE)
Form			Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~90% (SDS-PAGE)
Description			FGFR4, as known as fibroblast growth factor receptor 4 isoform 1, is a glycosylated transmembrane receptor tyrosine kinase. This protein is widely expressed during embryonic development and in adult liver, kidney, and lung. Also, it is associates with beta-Klotho and sulfated glycosaminoglycans, and these interactions increase the affinity of FGFR4 for its ligands as well as its signaling capacity. This receptor signaling is additionally required for skeletal muscle development in limbs. Source: Recombinant protein corresponding to aa22-369 from human FGFR4, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~39.5kD (356aa) 40-57kD (SDS-PAGE under reducing conditions) Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.