NECTIN2, Recombinant, Human, aa32-360, His-Tag (Nectin-2, CD112, HVEB, PRR2, PVRL2, PVRR2)

Catalog No : USB-377897
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Product name NECTIN2, Recombinant, Human, aa32-360, His-Tag (Nectin-2, CD112, HVEB, PRR2, PVRL2, PVRR2)
Catalog No USB-377897
Supplier’s Catalog No 377897
Supplier US Biologicals
Source antigen Recombinant, Baculovirus
Reactivity
Cross reactivity
Applications
Molecular weight 36.3
Storage -20°C
Other names
Grade Highly Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description NECTIN2, also known as nectin-2 isoform delta, is a Ca(2+)-independent cell-cell adhesion molecule that is one of the plasma membrane components of adherens junctions. It is a key player for the establishment of homotypic and heterotypic cell to cell contacts. It is required for exerting the resistance against herpes simplex virus type 2 infection in transfected cells. It is a potential target for antibody therapy of breast and ovarian cancers. It might be associated with human longevity. Source: Recombinant protein corresponding to aa32-360 from human NECTIN2, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~36.3kD (337aa), 40-57kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: QDVRVQVLPE VRGQLGGTVE LPCHLLPPVP GLYISLVTWQ RPDAPANHQN VAAFHPKMGP SFPSPKPGSE RLSFVSAKQS TGQDTEAELQ DATLALHGLT VEDEGNYTCE FATFPKGSVR GMTWLRVIAK PKNQAEAQKV TFSQDPTTVA LCISKEGRPP ARISWLSSLD WEAKETQVSG TLAGTVTVTS RFTLVPSGRA DGVTVTCKVE HESFEEPALI PVTLSVRYPP EVSISGYDDN WYLGRTDATL SCDVRSNPEP TGYDWSTTSG TFPTSAVAQG SQLVIHAVDS LFNTTFVCTV TNAVGMGRAE QVIFVRETPN TAGAGATGGL EHHHHHH Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.