IFNGR1, Recombinant, Human, aa18-245, His-Tag (IFNGR1, CD119, IFNGR, IMD27A, IMD27B, Interferon Gamma Receptor 1)
Catalog No : USB-470238
508.06€
0.00€
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| Product name | IFNGR1, Recombinant, Human, aa18-245, His-Tag (IFNGR1, CD119, IFNGR, IMD27A, IMD27B, Interferon Gamma Receptor 1) | ||
|---|---|---|---|
| Catalog No | USB-470238 | ||
| Supplier’s Catalog No | 470238 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Insect Cell | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 26.6284 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~90% (SDS-PAGE) | ||
| Form | Supplied as a liquid in PBS, pH 7.4, 10% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ~90% (SDS-PAGE) | ||
| Description | IFNGR1, also known as interferon gamma receptor 1, is a member of the hematopoietic cytokine receptor superfamily. It is a receptor that binds interferon-gamma, the sole member of interferon type II. It induces the rapid dimerization of chains, thereby forming a site that is recognized by the extracellular domain of IFNGR2. It is expressed in a membrane-bound form in many cell types, and is over-expressed in tumour cells. Its signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6. It is crucial for host defence against mycobacterial infections. It is associated with susceptibility to pulmonary tuberculosis (TB). Source: Recombinant protein corresponding to aa18-245 from human IFNGR1, fused to His-Tag at C-terminal, expressed in Insect Cell. Molecular Weight: ~26.6kD (234aa) ~28-40kD (SDS-PAGE under reducing conditions) AA Sequence: EMGTADLGPS SVPTPTNVTI ESYNMNPIVY WEYQIMPQVP VFTVEVKNYG VKNSEWIDAC INISHHYCNI SDHVGDPSNS LWVRVKARVG QKESAYAKSE EFAVCRDGKI GPPKLDIRKE EKQIMIDIFH PSVFVNGDEQ EVDYDPETTC YIRVYNVYVR MNGSEIQYKI LTQKEDDCDE IQCQLAIPVS SLNSQYCVSA EGVLHVWGVT TEKSKEVCIT IFNSSIKGHH HHHH Endotoxin: <1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | ||
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