ALK4, Recombinant, Human, GST-Tag (ACVR1B, SKR2, ACTRIB, ACVRLK4)
Catalog No : USB-499774
572.43€
0.00€
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| Product name | ALK4, Recombinant, Human, GST-Tag (ACVR1B, SKR2, ACTRIB, ACVRLK4) | ||
|---|---|---|---|
| Catalog No | USB-499774 | ||
| Supplier’s Catalog No | 499774 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Insect cells | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 64 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Purified | ||
| Purity | Purified (~70-90%) | ||
| Form | Supplied as a liquid in 50mM Tris-HCl, pH 7.5, 150mM sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | Purified (~70-90%) | ||
| Description | ALK4 is a member of the subfamily of receptor ser/thr kinases that mediates signaling by the Activins. ALK4 is expressed in many human tissues, including kidney, pancreas, brain, lung, and liver. Truncated ALK4, predominantly expressed in human pituitary adenomas, function as dominant negative receptors to interfere with wild-type receptor function and blocks the antiproliferative effect of activin possibly contributing to development of human pituitary tumors. ALK4 is able to mediate Nodal signaling in the presence of Cripto during vertebrate development. Source: Recombinant protein corresponding to human ALK4, fused to GST-Tag at N-terminal, expressed in Insect cells. Molecular Weight: ~64kD Specific Activity: 16nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | ||
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