Chemerin, Recombinant, Human (RARRES2, RAR-Responsive Protein TIG2, Tazarotene-Induced Gene 2 Protein, Retinoic Acid Receptor Responder Protein 2)
Catalog No : USB-499881
491.97€
0.00€
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| Product name | Chemerin, Recombinant, Human (RARRES2, RAR-Responsive Protein TIG2, Tazarotene-Induced Gene 2 Protein, Retinoic Acid Receptor Responder Protein 2) | ||
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| Catalog No | USB-499881 | ||
| Supplier’s Catalog No | 499881 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 16 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~95% (SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder in PBS. Reconstitute with 250ul sterile PBS. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ~95% (SDS-PAGE) | ||
| Description | Human Chemerin, also known as Tazarotene induced Gene 2 (TIG2), is an adipokine that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1. Its other ligands include G protein-coupled receptor 1 and chemokine receptor-like 2. Chemerin is expressed in various tissues where its biologically active form is generated by proteolytic removal of C-terminal residues by circulating proteases. In human, the soluble protoform gets processed into a monomeric, heparin binding bioactive molecule that can have both pro- and anti-inflammatory properties depending on the modality of enzymatic cleavage by different classes of proteases. Source: Recombinant protein corresponding to human Chemerin expressed in E. coli. Molecular Weight: ~16kD Biological Activity: Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human ChemR23. The ED50 for this effect is typically 4-20ng/mL. Endotoxin: <1EU/ug (LAL) Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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