IRR, Recombinant, Human, GST-Tag (Insulin Receptor-Related Receptor, INSRR)

Catalog No : USB-500186
572.43€
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Product name IRR, Recombinant, Human, GST-Tag (Insulin Receptor-Related Receptor, INSRR)
Catalog No USB-500186
Supplier’s Catalog No 500186
Supplier US Biologicals
Source antigen Recombinant, Insect cells
Reactivity
Cross reactivity
Applications
Molecular weight 65
Storage -70°C
Other names
Grade Purified
Purity Purified (~70-90%)
Form Supplied as a liquid in 50mM Tris-HCl, pH 7.5, 150mM sodium chloride, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity Purified (~70-90%)
Description IRR or insulin receptor-related receptor is a tyrosine protein kinase that is required for the appearance of male gonads and thus for male sexual differentiation. The expression of IRR mRNA is restricted to a few tissue types and has been detected in neuronal tissues as well as in neuroblastomas. As a result of its occurrence in neuroblastomas, it has speculated that IRR may be involved in tumor genesis. RT-PCR and solution hybridization/RNAse protection assay have shown strong coupling of IRR mRNA in 18 tumor cell lines. Source: Recombinant protein corresponding to human IRR, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~65kD Specific Activity: 111nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.