ACVR1, GST-Tag, Recombinant (FOP, ALK2, SKR1, TSRI, ACTRI, ACVR1A, ACVRLK2, Activin Receptor Type-1)
Catalog No : USB-500583
482.77€
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| Product name | ACVR1, GST-Tag, Recombinant (FOP, ALK2, SKR1, TSRI, ACTRI, ACVR1A, ACVRLK2, Activin Receptor Type-1) | ||
|---|---|---|---|
| Catalog No | USB-500583 | ||
| Supplier’s Catalog No | 500583 | ||
| Supplier | US Biologicals | ||
| Source antigen | E. coli, Recombinant | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 50 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Lysate | ||
| Purity | Lysate | ||
| Form | Supplied as a lyophilized powder in Tris-HCl, pH 6.8, 0.2M DTT, 4% SDS, 0.2% bromophenol blue, 20% sucrose. Reconstitute with 200ul sterile dH2O. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | Lysate | ||
| Description | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. Source: Partial length protein corresponding to of ACVR1, fused to GST-Tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Molecular Weight: ~50kD Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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