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Categories: Peptides & Proteins / Proteins

Product name			GLRB, GST-Tag, Recombinant (GLRB, Glycine Receptor Subunit Beta)
Catalog No			USB-500749
Supplier’s Catalog No			500749
Supplier			US Biologicals
Source antigen			E. coli, Recombinant
Reactivity
Cross reactivity
Applications
Molecular weight

Storage			-20°C
Other names
Grade			Lysate
Purity			Lysate
Form			Supplied as a lyophilized powder in Tris-HCl, pH 6.8, 0.2M DTT, 4% SDS, 0.2% bromophenol blue, 20% sucrose. Reconstitute with 200ul sterile dH2O.
Reactivity life			6 months
Note			For reserch purpose only
Purity			Lysate
Description			This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. Source: Partial length protein corresponding to of GLRB, fused to GST-Tag, expressed in E. coli. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.