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Categories: Peptides & Proteins / Proteins

Product name			CHRNA6, Recombinant, Human, aa26-239, His-Tag (Cholinergic Receptor, Nicotinic, alpha)
Catalog No			USB-218035
Supplier’s Catalog No			218035
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			29.3

Storage			-20°C
Other names
Grade			Purified
Purity			~85% (SDS-PAGE)
Form			Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.4M urea, 10% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~85% (SDS-PAGE)
Description			Cholinergic receptor, nicotinic, alpha 6, also known as CHRNA6, belongs to the nicotinic acetylcholine receptors (nAChRs) family. nAChRs are heteropentameric ligand-gated ion channels resulting from the assembly of alpha and beta protein subunits. This ion channel is gated by the binding of acetylcholine to the assembled receptor. Alpha 6 is often found associated with beta 3, beta 2, and alpha 4 subunits. CHRNA6 receptors have a relatively selective localization to the nigrostriatal pathway where they function to mediate dopamine release. Source: Recombinant corresponding to aa26-239 from human CHRNA6 protein, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~29.3kD (250aa) Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.