Uteroglobin, Recombinant, Human (SCGB1A1, Clara Cell Phospholipid-binding Protein, CCPBP, Clara Cells 10kD Secretory Protein, CC10, Secretoglobin Family 1A Member 1, Urinary Protein 1, UP-1, UP1, Urine Protein 1, CC10, CCSP, UGB)
Catalog No : USB-143532
354.03€
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| Product name | Uteroglobin, Recombinant, Human (SCGB1A1, Clara Cell Phospholipid-binding Protein, CCPBP, Clara Cells 10kD Secretory Protein, CC10, Secretoglobin Family 1A Member 1, Urinary Protein 1, UP-1, UP1, Urine Protein 1, CC10, CCSP, UGB) | ||
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| Catalog No | USB-143532 | ||
| Supplier’s Catalog No | 143532 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥98% by SDS-PAGE gel and HPLC analyses. | ||
| Form | Supplied as a lyophilized powder. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥98% by SDS-PAGE gel and HPLC analyses. | ||
| Description | Uteroglobin, a member of the Secretoglobin superfamily, also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation. Recombinant Human Uteroglobin is an 8kD homodimeric protein consisting of 142aa residues. AA Sequence: MEICPSFQRV IETLLMDTPS SYEAAMELFS PDQDMREAGA QLKKLVDTLP QKPRESIIKL MEKIAQSSLC N Quality Control: Verified by N-terminal and Mass Spectrometry analyses (when applicable). Endotoxin: <0.1ng/ug of protein (<1EU/ug). Protein Content: Verified by UV Spectroscopy and/or SDS-PAGE gel. Storage and Stability: Store lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein. | ||
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