Uteroglobin, Recombinant, Human (Clara Cell Phospholipid-binding Protein, CCPBP, Clara Cells 10kD Secretory Protein, CC10, Secretoglobin Family 1A Member 1, Urinary Protein 1, UP-1, UP1, Urine Protein 1)
Catalog No : USB-220424
381.62€
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| Product name | Uteroglobin, Recombinant, Human (Clara Cell Phospholipid-binding Protein, CCPBP, Clara Cells 10kD Secretory Protein, CC10, Secretoglobin Family 1A Member 1, Urinary Protein 1, UP-1, UP1, Urine Protein 1) | ||
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| Catalog No | USB-220424 | ||
| Supplier’s Catalog No | 220424 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 8 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~98% (SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder in PBS. No preservative added. Reconstitute with sterile ddH2O to 0.1-1mg/ml. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~98% (SDS-PAGE) | ||
| Description | Uteroglobin, a member of the Secretoglobin superfamily, also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation. Source: Recombinant protein corresponding to 142aa residues from human Uteroglobin, expressed in E. coli. Molecular Weight: ~8kD Endotoxin: <0.1ng/ug of protein (<1EU/ug) AA Sequence: MEICPSFQRV IETLLMDTPS SYEAAMELFS PDQDMREAGA QLKKLVDTLP QKPRESIIKL MEKIAQSSLC N Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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