SCGB1A1, Canine

Catalog No : USB-471589
365.53€
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Product name SCGB1A1, Canine
Catalog No USB-471589
Supplier’s Catalog No 471589
Supplier US Biologicals
Source antigen E. coli, canine
Reactivity
Cross reactivity
Applications
Molecular weight
Storage -20°C
Other names
Grade Molecular Biology Grade
Purity
Form Supplied as a liquid in PBS.
Reactivity life 6 months
Note For reserch purpose only
Purity
Description Uteroglobin (SCGB1A1) which belongs to the Secretoglobin (SCGBs) superfamily, is a multifunctional protein that exerts anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. Uteroglobin is involved in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. SCGB1A1 is expressed by Clara cells, the non-ciliated, non-mucous secretory cells predominant in lung bronchioles, and by other epithelia which communicate with the external environment. On top of sequestering pro-inflammatory mediators and carcinogens, Uteroglobin is implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation. SCGB1A1 gene defects are associated with a susceptibility to asthma. Source: Canine SCGB1A1, from E. coli Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.