Imugex

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Categories: Peptides & Proteins / Proteins

Product name			SEPX1, SelCys95Cys, Recombinant, Human (Methionine-R-sulfoxide Reductase B1, MsrB1, Selenoprotein X, SelX, MSRB1, HSPC270)
Catalog No			USB-S0950-80
Supplier’s Catalog No			S0950-80
Supplier			US Biologicals
Source antigen			Recombinant, E.coli
Reactivity
Cross reactivity
Applications
Molecular weight			12.8

Storage			-20°C
Other names
Grade			Highly Purified
Purity			~95% (SDS-PAGE)
Form			Supplied as a lyophilized powder from 20mM HEPES, pH 7.4. Reconstitute with sterile dH2O PBS.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~95% (SDS-PAGE)
Description			Methionine sulfoxide reductase B (MsrB), also known as SelX, is a selenoprotein. The oxidation of methionine at the sulfur atom leads to alternative epimers: R form of Met(O) and S form of Met(O). MsrB can reduce R form of both free and protein-incorporated methionine sulfoxide to methionine. It has a crucial role in protecting cells against oxidative damages. MsrA reduces only the S epimer of Met(O), and MsrB reduces the R epimer of Met(O) in proteins. Although the catalytic mechanisms of MsrA and MsrB are similar, two Msrs have no sequence identity and no structural similarity. Source: Recombinant corresponding to aa1-116, from human MsrB, expressed in E.coli. Molecular Weight: ~12.8kD Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.