SAA1, Recombinant, Monkey (Serum Amyloid A1, Serum Amyloid A Protein, SAA, Amyloid Protein A, Amyloid Fibril Protein AA, SAA1, SAA2, PIG4, TP53I4, MGC111216)
Catalog No : USB-220241
539.10€
0.00€
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| Product name | SAA1, Recombinant, Monkey (Serum Amyloid A1, Serum Amyloid A Protein, SAA, Amyloid Protein A, Amyloid Fibril Protein AA, SAA1, SAA2, PIG4, TP53I4, MGC111216) | ||
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| Catalog No | USB-220241 | ||
| Supplier’s Catalog No | 220241 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 11.8 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~97% (SDS-PAGE, HPLC) | ||
| Form | Supplied as a lyophilized powder in PBS, pH 7.4. No preservative added. Reconstitute with sterile ddH2O to ≥100ug/ml. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~97% (SDS-PAGE, HPLC) | ||
| Description | SAA1 protein is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 (Serum amyloid A1) protein is produced mainly in the liver and circulates in low levels in the blood. The SAA1 seems to have a role in the immune system. SAA1 protein levels increase in the blood and other tissues under conditions of inflammation. SAA1 may facilitate the repair of injured tissues; it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex. Elevated levels of SAA1 ultimately affect secondary amyloidosis, extracellular amassing of amyloid fibrils, resulting from a circulating precursor, in a variety of tissues and organs. The most widespread type of amyloidosis appears secondary to chronic inflammatory disease, mainly rheumatoid arthritis. SAA1 is purified by proprietary chromatographic techniques. Source: Recombinant protein corresponding to monkey SAA1, a single, non-glycosylated, polypeptide chain containing 104aa, expressed in E. coli. Molecular Weight: ~11.8kD Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 1-10ng/ml. AA Sequence: RSWFSFLGEA YDGARDMWRA YSDMKEANYK NSDKYFHARG NYDAAQRGPG GVWAAEVISD ARENIQKLLG RGAEDTLADQ AANEWGRSGK DPNHFRPAGL PEKY Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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