Haptoglobin, Human, Phenotype 2-2 (Alpha Polypeptide, HP, Hp2 alpha, Beta Polypeptide, HPT, HPA1S, HP2 alpha2)
Catalog No : USB-301367
508.06€
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| Product name | Haptoglobin, Human, Phenotype 2-2 (Alpha Polypeptide, HP, Hp2 alpha, Beta Polypeptide, HPT, HPA1S, HP2 alpha2) | ||
|---|---|---|---|
| Catalog No | USB-301367 | ||
| Supplier’s Catalog No | 301367 | ||
| Supplier | US Biologicals | ||
| Source antigen | Human plasma | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 170000900000 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥95% (SDS-PAGE). No visible alpha-1 light chain. | ||
| Form | Supplied as a salt-free, lyophilized powder. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥95% (SDS-PAGE). No visible alpha-1 light chain. | ||
| Description | An acute-phase plasma protein found in human plasma at 100-300mg/100ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes. Hp 1-1 is the most common, and the most effective in binding free hemoglobin. Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype. Hp 2-2 is associated with renal failure, familial epilepsy, hypertension, atherosclerosis and coronary heart diseases. Individuals who are phenotype 2-2 have the lowest concentration of haptoglobin in plasma. Source: Native Haptoglobin, from human plasma Purity: ≥95% (SDS-PAGE). No visible alpha-1 light chain. Molecular Weight:: 170,000-900,000 Extinction Coefficient: 1.20 Source: Native Source: Native Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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