ASCC3, Recombinant, Human, aa1-111, GST-Tag (Activating Signal Cointegrator 1 Complex Subunit 3)

Catalog No : USB-372351
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Product name ASCC3, Recombinant, Human, aa1-111, GST-Tag (Activating Signal Cointegrator 1 Complex Subunit 3)
Catalog No USB-372351
Supplier’s Catalog No 372351
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 40
Storage -20°C
Other names
Grade Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in Tris, 50% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation. Source: Recombinant protein corresponding to aa1-111 from human ASCC3, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~40.0kD AA Sequence: MALPRLTGALRSFSNVTKQDNYNEEVADLKIKRSKLHEQVLDLGLTWKKIIKFLNEKLEKSKMQSINEDLKDILHAAKQIEVNCPFQKRRLDGKEEDEKMSRASDRFRGLR Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.