COP9 Signalosome Complex Subunit 2, Recombinant, Danio Rerio, aa1-443, His-Tag (cops2)

Catalog No : USB-405897
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Product name COP9 Signalosome Complex Subunit 2, Recombinant, Danio Rerio, aa1-443, His-Tag (cops2)
Catalog No USB-405897
Supplier’s Catalog No 405897
Supplier US Biologicals
Source antigen Recombnant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 57.1
Storage -20°C
Other names
Grade Purified
Purity ~85% (SDS-PAGE)
Form Supplied as a liquid in Tris, 50% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~85% (SDS-PAGE)
Description Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity.. Source: Recombinant full length protein corresponding to aa1-443 from Danio Rerio COP9 Signalosome Complex Subunit 2, fused to His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~57.1kD AA Sequence: MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEFGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTINGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAIVSKLA Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.