SIRT6, Recombinant, Human, aa1-355, His-Tag (Sirtuin 6, SIR2L6, Mono-ADP-ribosyltransferase Sirtuin-6, SIR2-like protein 6)

Catalog No : USB-351496
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Product name SIRT6, Recombinant, Human, aa1-355, His-Tag (Sirtuin 6, SIR2L6, Mono-ADP-ribosyltransferase Sirtuin-6, SIR2-like protein 6)
Catalog No USB-351496
Supplier’s Catalog No 351496
Supplier US Biologicals
Source antigen Recombinant, human from E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 41
Storage -20°C/-70°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol.
Reactivity life 12 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description The SIRT6 is included in class IV of the sirtuin family, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined; however, in yeast sirtuins are known to regulate epigenetic gene silencing. Also SIRT6, a chromatin-associated protein, appears to be involved in DNA repair. Source: Recombinant protein corresponding to aa1-355 from human SIRT6, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~41kD (375aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MSVNYAAGLS PYADKGKCGL PEIFDPPEEL ERKVWELARL VWQSSSVVFH TGAGISTASG IPDFRGPHGV WTMEERGLAP KFDTTFESAR PTQTHMALVQ LERVGLLRFL VSQNVDGLHV RSGFPRDKLA ELHGNMFVEE CAKCKTQYVR DTVVGTMGLK ATGRLCTVAK ARGLRACRGE LRDTILDWED SLPDRDLALA DEASRNADLS ITLGTSLQIR PSGNLPLATK RRGGRLVIVN LQPTKHDRHA DLRIHGYVDE VMTRLMEHLG LEIPAWDGPR VLERALPPLP RPPTPKLEPK EESPTRINGS IPAGPKQEPC AQHNGSEPAS PKRERPTSPA PHRPPKRVKA KAVPS Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.