Indian hedgehog, active (IHH), Recombinant, Human
Catalog No : USB-348069
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| Product name | Indian hedgehog, active (IHH), Recombinant, Human | ||
|---|---|---|---|
| Catalog No | USB-348069 | ||
| Supplier’s Catalog No | 348069 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Human, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 19.8 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥96% as determined by SDS-PAGE and HPLC. | ||
| Form | Lyophilized from 0.2um filtered 20mM PBS, pH 7.4, 150mM NaCl | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥96% as determined by SDS-PAGE and HPLC. | ||
| Description | Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 3.0-10ug/ml. Sequence: IIGPGRVVGS RRRPPRKLVP LAYKQFSPNV PEKTLGASGR YEGKIARSSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDRLNSLAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRNKYGLL ARLAVEAGFD WVYYESKAHV HCSVKSEHSA AAKTGG Molecular Weight: 19.8kD PubMed ID: 15489334; 7590746; 7720571; 9593755; 16335952; 20519495; 21537345; 11455389; 12384778; 12632327 Gene Name: IHH Swiss Prot: Q14623 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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