Superoxide Dismutase, MN, Recombinant, Human (SOD Mn)
Catalog No : USB-S8060-25N
668.98€
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| Product name | Superoxide Dismutase, MN, Recombinant, Human (SOD Mn) | ||
|---|---|---|---|
| Catalog No | USB-S8060-25N | ||
| Supplier’s Catalog No | S8060-25N | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant Mn SOD (Human) Protein, His-Tag, E. coli. | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Affinity Purified | ||
| Purity | ≥90% by affinity chromatography | ||
| Form | ≥90% (SDS-PAGE). Purified by affinity chromatography | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥90% by affinity chromatography | ||
| Description | Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2¯ to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase. In general, SODs play a major role in antioxidant defense mechanisms. There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16kD each are linked by two cysteines forming an intra-subunit disulfide bridge. The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80kD. The third form (SOD3 or ECSOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30kD and it exists only in the extracellular space. SOD3 can also be distinguished by its heparin-binding capacity. Recombinant protein corresponding to human Mn SOD containing a 6-His-Tag, expressed in E. coli. GeneBank Accession Number: BC070913 Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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