SOD1, Recombinant, Human, aa1-154 (Superoxide dismutase 1, soluble, ALS, SOD, ALS1, IPOA, Cu-Zn superoxide dismutase)
Catalog No : USB-351501
508.06€
0.00€
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| Product name | SOD1, Recombinant, Human, aa1-154 (Superoxide dismutase 1, soluble, ALS, SOD, ALS1, IPOA, Cu-Zn superoxide dismutase) | ||
|---|---|---|---|
| Catalog No | USB-351501 | ||
| Supplier’s Catalog No | 351501 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, human from E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 15.9 | ||
| Storage | -20°C/-70°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~95% (SDS-PAGE) | ||
| Form | Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 10% glycerol. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~95% (SDS-PAGE) | ||
| Description | Superoxide dismutase 1 (SOD1) binds copper and zinc ions and is one of three isozymes responsible for destroying free superoxide radicals in the body. The encoded protein neutralizes supercharged oxygen molecules, which can damage cells if their levels are not controlled. Mutations in SOD1 cause a form of familial amyotrophic lateral sclerosis (ALS). Source: Recombinant protein corresponding to aa1-154 from human SOD1 expressed in E. coli. Molecular Weight: ~15.9kD (154aa) Specific Activity: >1000units/mg, in which one unit will inhibit the rate of reduction of cytochrome c by 50% in a coupled system, using xanthine and Xanthine oxidase at pH 7.5 at 25°C. AA Sequence: MATKAVCVLK GDGPVQGIIN FEQKESNGPV KVWGSIKGLT EGLHGFHVHE FGDNTAGCTS AGPHFNPLSR KHGGPKDEER HVGDLGNVTA DKDGVADVSI EDSVISLSGD HCIIGRTLVV HEKADDLGKG GNEESTKTGN AGSRLACGVI GIAQ Endotoxin: ~1EU/1ug of protein (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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