Synuclein, alpha (SNCA), Human, Recombinant

Catalog No : USB-506383
1135.66€
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Product name Synuclein, alpha (SNCA), Human, Recombinant
Catalog No USB-506383
Supplier’s Catalog No 506383
Supplier US Biologicals
Source antigen E. coli, BL21DE3
Reactivity
Cross reactivity
Applications
Molecular weight 15
Storage -20°C
Other names
Grade Highly Purified
Purity ≥95%
Form Supplied as a liquid in 50mM PBS, pH 7.4, 150mM NaCl, 2mM PMSF, 1mM AEBSF, 25% glycerol.
Reactivity life
Note For reserch purpose only
Purity ≥95%
Description α-Synuclein is a major component of Parkinson’s disease aggregates and is implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders. α-Synuclein accumulates in the brains of sporadic Parkinson’s disease patients as a major component of Lewy bodies, which are intra-neuronal cytoplasmic inclusions characteristic of Parkinson’s disease. α-Synuclein appears to associate with other proteins that aggregate and is found in β-amyloid plaques and neuritic tangles in Alzheinmer’s disease. Recombinant α-Synuclein is expressed in E. coli strain and purified by column chromatography. Recombinant protein corresponding to human Alpha Synuclein, expressed in Transformed E. coli. Molecular Weight: ~15kD Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.