VTCN1, Recombinant, Human, aa25-259, His-Tag (B7H4, V-Set Domain Containing T Cell Activation Inhibitor 1)

Catalog No : USB-218672
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Product name VTCN1, Recombinant, Human, aa25-259, His-Tag (B7H4, V-Set Domain Containing T Cell Activation Inhibitor 1)
Catalog No USB-218672
Supplier’s Catalog No 218672
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 28.2
Storage -20°C
Other names
Grade Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.4M urea, 10% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description The VCTN1 is a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. Source: Recombinant corresponding to aa25-259 from human VTCN1 protein, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~28.2kD (258aa) Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.