Alpha-insect Toxin LqhaIT, Recombinant, Leiurus Quinquestriatus Hebraeus, aa20-85, His-Tag

Catalog No : USB-370514
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Product name Alpha-insect Toxin LqhaIT, Recombinant, Leiurus Quinquestriatus Hebraeus, aa20-85, His-Tag
Catalog No USB-370514
Supplier’s Catalog No 370514
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 23.52
Storage -20°C
Other names
Grade Purified
Purity ~85% (SDS-PAGE)
Form Supplied as a liquid in Tris, 50% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~85% (SDS-PAGE)
Description Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. The dissociation is voltage-dependent. This toxin is active on insects. It is also highly toxic to crustaceans and has a measurable but low toxicity to mice. Source: Recombinant protein corresponding to aa20-85 from Leiurus quinquestriatus hebraeus, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~23.52kD AA Sequence: VRDAYIAKNYNCVYECFRDAYCNELCTKNGASSGYCQWAGKYGNACWCYALPDNVPIRVPGKCHRK Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.