Imugex

Shipping cost plus VAT not included , delivery in 7-14 business days

Categories: Peptides & Proteins / Proteins

Product name			MOP3, Human, Control Peptide (Members of PAS Superfamily, BMAL1, Brain And Muscle ARNT-like 1, JAP3, PAS3, CYCLE)
Catalog No			USB-M4591-02B
Supplier’s Catalog No			M4591-02B
Supplier			US Biologicals
Source antigen			Human synthetic peptide
Reactivity			100% conserved in related proteins from other species. Control peptide, because of its low MW (<3kD), is not suitable for Western
Cross reactivity
Applications
Molecular weight

Storage			-20°C
Other names
Grade			Highly Purified
Purity			Highly purified
Form			Supplied as a liquid in PBS, pH 7.2
Reactivity life			12 months
Note			For reserch purpose only
Purity			Highly purified
Description			A 15-aa peptide sequence within the C-terminus of Human MOP3. Circadian rhythm is one of the most fascinating and complex biological phenomenon's. The circadian clock controls biological activities on daily light-dark cycles in species from cyanobacteria to humans. The circadian clock has three major components: A photoactive pigment (chromophore) for sensing light and transmitting light signals, the circadian clock that oscillates every ~24-hrs, and the genes controlled by the circadian clock to bring about the physiological and behavioral changes. Several genes (Drosophila Clock Per, Tim; mammalian Per1, Per2, Per3, MOP3 and MOP4, and BMAL1) have been linked to rhythmicity or circadian behavior of living organisms. However, very little is known about the mammalian photosensory molecules. Basic-helix-loop-helix-PAS orphan protein, MOP3 (Members Of PAS Superfamily; also known as BMAL1/JAP3/PAS3; 626 aa) is a general dimerization partner for several PAS superfamily of transcription regulators. MOP3 interacts with MOP4 (also known as NPAS2; 626 aa), Clock, HIF1a, and HIF2a. MOP4 is a brain specific homolog of Clock.