CEBP alpha, aa270-358, bZIP Region, Recombinant, Human, His-Tag (CCAAT Enhancer Binding Protein, alpha)
Catalog No : USB-C2589-88
695.42€
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| Product name | CEBP alpha, aa270-358, bZIP Region, Recombinant, Human, His-Tag (CCAAT Enhancer Binding Protein, alpha) | ||
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| Catalog No | USB-C2589-88 | ||
| Supplier’s Catalog No | C2589-88 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Human (E. coli) | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥ 95% by SDS PAGE; Purified by ion-exchange chromatography and FPLC gel-filtration chromatography. | ||
| Form | Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 0.1M sodium chloride, 5mM beta-Mercaptoethanol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥ 95% by SDS PAGE; Purified by ion-exchange chromatography and FPLC gel-filtration chromatography. | ||
| Description | CCAAT/enhancer binding protein (C/EBP) alpha is a family of transcription factors that all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP family consist of several related proteins, C/EBP alpha, beta, gamma, delta, that form homodimers and that form heterodimers with each other. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein; a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. C/EBPs differ significantly in their physiological functions and in their downstream target genes. For example, mice lacking C/EBP alpha die shortly after birth due to severe hypoglycemia and the absence of glycogen storage in liver, whereas knockout of C/EBP beta causes defects in female reproduction. Molecular Weight: 14.5kD (126 amino acids) Sequence: MRGSHHHHHH/ GMASMTGGQQ/ MGRDLYDDDD/ KDRWGSMGAG/ KAKKSVDKNS/ NEYRVRRERN/ NIAVRKSRDK/ AKQRNVETQQ/ KVLELTSDND/ RLRKRVEQLS/ RELDTLRGIF/ RQLPESSLVK/ AMGNCA Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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