FOXQ1 Control Peptide (KLH) (Forkhead box Q1, FKHRL1, Hepatocyte Nuclear Factor 3 Forkhead, HFH1, Winged Helix/Forkhead Transcription Factor)
Catalog No : USB-F9050-26PK
348.29€
0.00€
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| Product name | FOXQ1 Control Peptide (KLH) (Forkhead box Q1, FKHRL1, Hepatocyte Nuclear Factor 3 Forkhead, HFH1, Winged Helix/Forkhead Transcription Factor) | ||
|---|---|---|---|
| Catalog No | USB-F9050-26PK | ||
| Supplier’s Catalog No | F9050-26PK | ||
| Supplier | US Biologicals | ||
| Source antigen | |||
| Reactivity | Recognizes FOXQ1. Species Crossreactivity: Human and rodent. | ||
| Cross reactivity | Human, Rodent, | ||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | Highly purified (HPLC, MS) | ||
| Form | Supplied as a liquid in PBS. No preservative added. Conjugated with KLH. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | Highly purified (HPLC, MS) | ||
| Description | Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via this protein. The Forkhead family of transcription factors is involved in tumorigenesis in rhabdomyosarcoma and acute leukemias (1–3). Within the family, three members (FKHR, AFX and FKHRL1) have sequence similarity to the nematode homologue DAF-16, which has been shown to mediate signaling via a pathway involving IGFR1, PI3K and Akt (4–6). There are three Akt phosphorylation sites in the FKHR proteins: Thr24, Ser256 and Ser319. Phosphorylation of FKHR family members at these sites by Akt promotes cell survival and regulates the cell cycle. Phosphorylation regulates FKHR nuclear translocation and target gene transcription (7,8). Sequence (linear): RRPGPHLPYPVE Applications: Suitable for use in ELISA, Western Blotting, Immunoprecipitation, Immunohistochemistry and or Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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