CITED 2, Recombinant, Human (Cbp/p300-interacting Transactivator 2, CITED2, MSG-related Protein 1, MRG1, MRG-1, P35srj)

Catalog No : USB-C5675-06H
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Product name CITED 2, Recombinant, Human (Cbp/p300-interacting Transactivator 2, CITED2, MSG-related Protein 1, MRG1, MRG-1, P35srj)
Catalog No USB-C5675-06H
Supplier’s Catalog No C5675-06H
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 29.5
Storage -20°C
Other names
Grade Highly Purified
Purity ~ 90% (SDS-PAGE). Purified by using conventional chromatography techniques. Endotoxin: ≤ 1.0 EU /1ug of protein (LAL).
Form Supplied as a liquid in 20mM Tris HCl pH8.0, 0.1M NaCl, 1mM DTT, 50% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~ 90% (SDS-PAGE). Purified by using conventional chromatography techniques. Endotoxin: ≤ 1.0 EU /1ug of protein (LAL).
Description CITED2 is an important transcriptional cofactor involved in multiple organ development. It is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator and a proposed negative regulator for hypoxia-inducible factor (HIF)-1a through its competitive binding with HIF-1a to CBP/p300. CITED2 is necessary for mouse fetal liver hematopoiesis and is required for the proper formation of the hyaloid vasculature and for lens morphogenesis. Recombinant CITED2 protein was expressed in E. coli. Source: Recombinant corresponding to aa1-270 of human CITED2 6x His tagged expressed in E. coli. AA Sequence: MADHMMAMNH GRFPDGTNGL HHHPAHRMGM GQFPSPHHHQ QQQPQHAFNA LMGEHIHYGA GNMNATSGIR HAMGPGTVNG GHPPSALAPA ARFNNSQFMG PPVASQGGSL PASMQLQKLN NQYFNHHPYP HNHYMPDLHP AAGHQMNGTN QHFRDCNPKH SGGSSTPGGS GGSSTPGGSG SSSGGGAGSS NSGGGSGSGN MPASVAHVPA AMLPPNVIDT DFIDEEVLMS LVIEMGLDRI KELPELWLGQ NEFDFMTDFV CKQQPSRVSC LEHHHHHH Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.