CTBP-1, Recombinant, Human (C-Terminal Binding Protein 1, CTBP1, CTBP, BARS, MGC104684)

Catalog No : USB-C7947-01H
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Product name CTBP-1, Recombinant, Human (C-Terminal Binding Protein 1, CTBP1, CTBP, BARS, MGC104684)
Catalog No USB-C7947-01H
Supplier’s Catalog No C7947-01H
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 47.5
Storage -20°C
Other names
Grade Highly Purified
Purity ~ 90% (SDS-PAGE). Purified by using conventional chromatography techniques.
Form Supplied as a liquid in 20mM Tris HCl pH 8.0, 100mM NaCl, 10% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~ 90% (SDS-PAGE). Purified by using conventional chromatography techniques.
Description C-terminal-binding protein 1 isoform 1, also known as CtBP1, is expressed from embryo to adult. This protein binds to the C-terminus of adenovirus E1A. It is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. Also, CtBP1 associates in complexes with histone deacetylases (HDAC), the G9a histone methyltransferase, and LSD1 histone demethylase illustrating its role in transcriptional repression. Recombinant human CtBP1 was expressed in E. coli. Source: Recombinant corresponding to aa1- 440 of human CtBP1 expressed in E. coli. AA Sequence: MGSSHLLNKG LPLGVRPPIM NGPLHPRPLV ALLDGRDCTV EMPILKDVAT VAFCDAQSTQ EIHEKVLNEA VGALMYHTIT LTREDLEKFK ALRIIVRIGS GFDNIDIKSA GDLGIAVCNV PAASVEETAD STLCHILNLY RRATWLHQAL REGTRVQSVE QIREVASGAA RIRGETLGII GLGRVGQAVA LRAKAFGFNV LFYDPYLSDG VERALGLQRV STLQDLLFHS DCVTLHCGLN EHNHHLINDF TVKQMRQGAF LVNTARGGLV DEKALAQALK EGRIRGAALD VHESEPFSFS QGPLKDAPNL ICTPHAAWYS EQASIEMREE AAREIRRAIT GRIPDSLKNC VNKDHLTAAT HWASMDPAVV HPELNGAAYR YPPGVVGVAP TGIPAAVEGI VPSAMSLSHG LPPVAHPPHA PSPGQTVKPE ADRDHASDQL Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.