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Categories: Peptides & Proteins / Proteins

Product name			BST2, Recombinant, Human, aa50-161, His-Tag (Bone marrow stromal antigen 2, HM1.24 antigen, Tetherin, CD317)
Catalog No			USB-B3000-09G
Supplier’s Catalog No			B3000-09G
Supplier			US Biologicals
Source antigen			Recombinant, E.coli
Reactivity
Cross reactivity
Applications
Molecular weight			14.8

Storage			-20°C
Other names
Grade			Purified
Purity			~80% (SDS-PAGE)
Form			Supplied as a liquid in 20mM Tris-HCl buffer, pH8, 0.1Msodium chloride, 1mM DTT, 20% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~80% (SDS-PAGE)
Description			BST2, also known as bone marrow stromal antigen 2, is involved in the growth and development of B-cells. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. Initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, tetherin has also been shown to inhibit the release of other viruses such as the Lassa and Marburg virions. Also, this protein may play a role in B-cell activation in rheumatoid arthritis. Purified by using conventional chromatography. Source: Recombinant corresponding to aa50-161 of human BST2, fused to His-tag at N-terminal, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSEACRDGLR AVMECRNVTH LLQQELTEAQ KGFQDVEAQA ATCNHTVMAL MASLDAEKAQ GQKKVEELEG EITTLNHKLQ DASAEVERLR RENQVLSVRI ADKKYYPSSQ DSS Molecular Weight: ~14.8kD (133aa), confirmed by MALDI-TOF Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.