CNOT8, Recombinant, Human, aa1-292, His-Tag (CCR4-NOT Transcription Complex Subunit 8, CAF1, CALIF, hCAF1, POP2)

Catalog No : USB-137027
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Product name CNOT8, Recombinant, Human, aa1-292, His-Tag (CCR4-NOT Transcription Complex Subunit 8, CAF1, CALIF, hCAF1, POP2)
Catalog No USB-137027
Supplier’s Catalog No 137027
Supplier US Biologicals
Source antigen Recombinant, E.coli
Reactivity
Cross reactivity
Applications
Molecular weight 35.9
Storage -20°C
Other names
Grade Highly Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.15M NaCl, 10% glycerol, 1mM DTT.
Reactivity life 6 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description CNOT8 belongs to the CAF1 family. It is a ubiquitous transcription factor required for a diverse set of processes and functions as part of the CCR-NOT complex. The CCR4-NOT complex functions as general transcription regulation complex. This complex contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8 and binds BTG2. Source: Recombinant protein corresponding to human CNOT8, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~35.9kD (315aa) (MALDI-TOF) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPAALVE NSQVICEVWA SNLEEEMRKI REIVLSYSYI AMDTEFPGVV VRPIGEFRSS IDYQYQLLRC NVDLLKIIQL GLTFTNEKGE YPSGINTWQF NFKFNLTEDM YSQDSIDLLA NSGLQFQKHE EEGIDTLHFA ELLMTSGVVL CDNVKWLSFH SGYDFGYMVK LLTDSRLPEE EHEFFHILNL FFPSIYDVKY LMKSCKNLKG GLQEVADQLD LQRIGRQHQA GSDSLLTGMA FFRMKELFFE DSIDDAKYCG RLYGLGTGVA QKQNEDVDSA QEKMSILAII NNMQQ Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.