MAFF, Recombinant, Human, aa1-164, His-Tag (Transcription Factor MafF Isoform A, HMafF, U-MAF)

Catalog No : USB-137110
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Product name MAFF, Recombinant, Human, aa1-164, His-Tag (Transcription Factor MafF Isoform A, HMafF, U-MAF)
Catalog No USB-137110
Supplier’s Catalog No 137110
Supplier US Biologicals
Source antigen Recombinant, E.coli
Reactivity
Cross reactivity
Applications
Molecular weight 20.1
Storage -20°C
Other names
Grade Purified
Purity ~85% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0,10% glycerol, 0.4M urea.
Reactivity life 6 months
Note For reserch purpose only
Purity ~85% (SDS-PAGE)
Description MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. This protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. Source: Recombinant protein corresponding to human MAFF, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~20.1kD (187aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSVDPLS SKALKIKREL SENTPHLSDE ALMGLSVREL NRHLRGLSAE EVTRLKQRRR TLKNRGYAAS CRVKRVCQKE ELQKQKSELE REVDKLAREN AAMRLELDAL RGKCEALQGF ARSVAAARGP ATLVAPASVI TIVKSTPGSG SGPAHGPDPA HGPASCS Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.