TEF, Recombinant, Human, aa1-303, His-Tag (Thyrotroph Rmbryonic Factor Isoform 1)

Catalog No : USB-137228
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Product name TEF, Recombinant, Human, aa1-303, His-Tag (Thyrotroph Rmbryonic Factor Isoform 1)
Catalog No USB-137228
Supplier’s Catalog No 137228
Supplier US Biologicals
Source antigen Recombinant, E.coli
Reactivity
Cross reactivity
Applications
Molecular weight 35.6
Storage -20°C
Other names
Grade
Purity ~85% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0,10% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~85% (SDS-PAGE)
Description Thyrotroph embryonic factor isoform 1, also known as TEF, is a 303 amino acid nuclear transcription factor that belongs to the bZIP (basic region/leucine zipper) family and PAR (proline and acidic amino acid-rich) subfamily. TEF binds DNA as either a homodimer or heterodimer, and is known to transactivate the TSH beta promoter. TEF accumulates according to a robust circadian rhythm and has also been found to inhibit cell growth by down-regulating beta chain expression of cytokine receptors. Source: Recombinant protein corresponding to human TEF, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~35.6kD (326aa) (MALDI-TOF) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSDAGGG KKPPVDPQAG PGPGPGRAAG ERGLSGSFPL VLKKLMENPP REARLDKEKG KEKLEEDEAA AASTMAVSAS LMPPIWDKTI PYDGESFHLE YMDLDEFLLE NGIPASPTHL AHNLLLPVAE LEGKESASSS TASPPSSSTA IFQPSETVSS TESSLEKERE TPSPIDPNCV EVDVNFNPDP ADLVLSSVPG GELFNPRKHK FAEEDLKPQP MIKKAKKVFV PDEQKDEKYW TRRKKNNVAA KRSRDARRLK ENQITIRAAF LEKENTALRT EVAELRKEVG KCKTIVSKYE TKYGPL Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.