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Categories: Peptides & Proteins / Proteins

Product name			Ataxin 3, Active, Recombinant, Human, His-Tag (Ataxin-3, Machado-Joseph Disease Protein 1, Spinocerebellar Ataxia Type 3 Protein, ATXN3, ATX3, MJD, MJD1, SCA3)
Catalog No			USB-137254
Supplier’s Catalog No			137254
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			42.1

Storage			-70°C
Other names
Grade			Purified
Purity			Purified (~60%)
Form			Supplied as a liquid in 45mM Tris-HCl, pH 8.0, 124mM sodium chloride, 2.4mM potassium chloride, 225mM imidazole, 10% glycerol, 3mM DTT.
Reactivity life			6 months
Note			For reserch purpose only
Purity			Purified (~60%)
Description			ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Source: Recombinant corresponding to aa2-362 from human ATX3, fused to His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~42.1kD Applications: Suitable for for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.