Imugex

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Categories: Peptides & Proteins / Proteins

Product name			NRF2, Recombinant, Human, aa1-605, His-Tag (Nuclear Factor (Erythroid-Derived 2)-Like 2, NFE2L2)
Catalog No			USB-218401
Supplier’s Catalog No			218401
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			69.9

Storage			-20°C
Other names
Grade			Purified
Purity			~85% (SDS-PAGE)
Form			Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~85% (SDS-PAGE)
Description			Nuclear factor (erythroid-derived 2)-like 2, also known as NRF2, is a bZIP transcription factor that heterodimerize with Maf proteins to bind Mare sequences. The NRF proteins also bind the antioxidant response element (ARE) and are implicated in the regulation of detoxification enzymes and the oxidative stress response. NRF2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from its repressor protein, Keap1. Source: Recombinant protein corresponding to aa1-605 from human NRF2, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~69.9kD (625aa) Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.