Bromodomain Testis-specific Protein, Recombinant, Human, aa257-382, His-Tag (BrdT)

Catalog No : USB-219505
471.28€
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Product name Bromodomain Testis-specific Protein, Recombinant, Human, aa257-382, His-Tag (BrdT)
Catalog No USB-219505
Supplier’s Catalog No 219505
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 14.9
Storage -70°C
Other names
Grade Purified
Purity ~98% (SDS-PAGE)
Form Supplied as a liquid in 50mM Tris, pH 8.0, 150mM sodium chloride, 10% glycerol.
Reactivity life 12 months
Note For reserch purpose only
Purity ~98% (SDS-PAGE)
Description BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin. This recombinant protein includes Bromo 1 domain (aa257-382) with N-terminal His-tag. Source: Recombinant protein corresponding to aa257-382 from human Bromodomain Testis-specific Protein, fused to His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~14.9kD (126aa, aa257-382 + NT His Tag) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.