TCEAL7, Recombinant, Human, aa1-100, His-Tag (Transcription elongation factor A (SII)-like 7)

Catalog No : USB-350322
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Product name TCEAL7, Recombinant, Human, aa1-100, His-Tag (Transcription elongation factor A (SII)-like 7)
Catalog No USB-350322
Supplier’s Catalog No 350322
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 14.8
Storage -20°C
Other names
Grade Purified
Purity ~80% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.2M sodium chloride, 2mM DTT, 50% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~80% (SDS-PAGE)
Description TCEAL7 plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. It associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. This protein regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres) and telomerase-positive cell lines. Source: Recombinant protein corresponding to aa1-100 of human TCEAL7, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~14.8kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMQKPCK ENEGKPKCSV PKREEKRPYG EFERQQTEGN FRQRLLQSLE EFKEDIDYRH FKDEEMTREG DEMERCLEEI RGLRKKFRAL HSNHRHSRDR PYPI Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.