Imugex

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Categories: Peptides & Proteins / Proteins

Product name			AES, Recombinant, Human, aa1-197, His-Tag (Amino-terminal enhancer of split, AES-1, AES-2, ESP1, GRG, GRG5, TLE5)
Catalog No			USB-351060
Supplier’s Catalog No			351060
Supplier			US Biologicals
Source antigen			Recombinant, human from E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			24.1

Storage			-20°C/-70°C
Other names
Grade			Highly Purified
Purity			~95% (SDS-PAGE)
Form			Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 20% glycerol.
Reactivity life			12 months
Note			For reserch purpose only
Purity			~95% (SDS-PAGE)
Description			Amino-terminal enhancer of split, also known AES, belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. This protein is expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle. In addition, AES can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Source: Recombinant protein corresponding to aa1-197 from human AES, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~24.1kD (217aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MMFPQSRHSG SSHLPQQLKF TTSDSCDRIK DEFQLLQAQY HSLKLECDKL ASEKSEMQRH YVMYYEMSYG LNIEMHKQAE IVKRLNGICA QVLPYLSQEH QQQVLGAIER AKQVTAPELN SIIRQQLQAH QLSQLQALAL PLTPLPVGLQ PPSLPAVSAG TGLLSLSALG SQAHLSKEDK NGHDGDTHQE DDGEKSD Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.